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Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges

Significant progress has been made in understanding pharmacokinetics (PK), pharmacodynamics (PD), as well as toxicity profiles of therapeutic proteins in animals and humans, which have been in commercial development for more than three decades. However, in the PK arena, many fundamental questions re...

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Autores principales: Vugmeyster, Yulia, Xu, Xin, Theil, Frank-Peter, Khawli, Leslie A, Leach, Michael W
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342576/
https://ncbi.nlm.nih.gov/pubmed/22558487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v3.i4.73
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