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Inferring Genetic Interactions via a Data-Driven Second Order Model

Genetic/transcriptional regulatory interactions are shown to predict partial components of signaling pathways, which have been recognized as vital to complex human diseases. Both activator (A) and repressor (R) are known to coregulate their common target gene (T). Xu et al. (2002) proposed to model...

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Hlavní autoři: Jiang, Ci-Ren, Hung, Ying-Chao, Chen, Chung-Ming, Shieh, Grace S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342528/
https://ncbi.nlm.nih.gov/pubmed/22563331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00071
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