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Inferring genetic interactions via a nonlinear model and an optimization algorithm

BACKGROUND: Biochemical pathways are gradually becoming recognized as central to complex human diseases and recently genetic/transcriptional interactions have been shown to be able to predict partial pathways. With the abundant information made available by microarray gene expression data (MGED), no...

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Autori principali: Chen, Chung-Ming, Lee, Chih, Chuang, Cheng-Long, Wang, Chia-Chang, Shieh, Grace S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848194/
https://ncbi.nlm.nih.gov/pubmed/20184777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-16
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