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Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation
The 40S ribosomal S6 kinase 1 (S6K1) is an important regulator of cell growth. Expression of S6K1 is often elevated in breast cancer cells. However, the transcriptional mechanism of S6K1 overexpression is not understood. In this report, we demonstrate that estrogen activates expression of S6K1 via E...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342462/ https://ncbi.nlm.nih.gov/pubmed/22286763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.657 |
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