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A Regulatory Transcriptional Loop Controls Proliferation and Differentiation in Drosophila Neural Stem Cells

Neurogenesis is initiated by a set of basic Helix-Loop-Helix (bHLH) transcription factors that specify neural progenitors and allow them to generate neurons in multiple rounds of asymmetric cell division. The Drosophila Daughterless (Da) protein and its mammalian counterparts (E12/E47) act as hetero...

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Hlavní autoři: Yasugi, Tetsuo, Fischer, Anja, Jiang, Yanrui, Reichert, Heinrich, Knoblich, Juergen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013126/
https://ncbi.nlm.nih.gov/pubmed/24804774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097034
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