Lrp5 Is Not Required for the Proliferative Response of Osteoblasts to Strain but Regulates Proliferation and Apoptosis in a Cell Autonomous Manner

Although Lrp5 is known to be an important contributor to the mechanisms regulating bone mass, its precise role remains unclear. The aim of this study was to establish whether mutations in Lrp5 are associated with differences in the growth and/or apoptosis of osteoblast-like cells and their prolifera...

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Hlavní autoři: Javaheri, Behzad, Sunters, Andrew, Zaman, Gul, Suswillo, Rosemary F. L., Saxon, Leanne K., Lanyon, Lance E., Price, Joanna S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342322/
https://ncbi.nlm.nih.gov/pubmed/22567110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035726
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