Abnormal Intracellular Accumulation and Extracellular Aβ Deposition in Idiopathic and Dup15q11.2-q13 Autism Spectrum Disorders

BACKGROUND: It has been shown that amyloid ß (Aβ), a product of proteolytic cleavage of the amyloid β precursor protein (APP), accumulates in neuronal cytoplasm in non-affected individuals in a cell type–specific amount. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found that the percent...

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Detaylı Bibliyografya
Asıl Yazarlar: Wegiel, Jerzy, Frackowiak, Janusz, Mazur-Kolecka, Bozena, Schanen, N. Carolyn, Cook, Edwin H., Sigman, Marian, Brown, W. Ted, Kuchna, Izabela, Wegiel, Jarek, Nowicki, Krzysztof, Imaki, Humi, Ma, Shuang Yong, Chauhan, Abha, Chauhan, Ved, Miller, David L., Mehta, Pankaj D., Flory, Michael, Cohen, Ira L., London, Eric, Reisberg, Barry, de Leon, Mony J., Wisniewski, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342283/
https://ncbi.nlm.nih.gov/pubmed/22567102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035414
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