Abnormal Intracellular Accumulation and Extracellular Aβ Deposition in Idiopathic and Dup15q11.2-q13 Autism Spectrum Disorders

BACKGROUND: It has been shown that amyloid ß (Aβ), a product of proteolytic cleavage of the amyloid β precursor protein (APP), accumulates in neuronal cytoplasm in non-affected individuals in a cell type–specific amount. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found that the percent...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wegiel, Jerzy, Frackowiak, Janusz, Mazur-Kolecka, Bozena, Schanen, N. Carolyn, Cook, Edwin H., Sigman, Marian, Brown, W. Ted, Kuchna, Izabela, Wegiel, Jarek, Nowicki, Krzysztof, Imaki, Humi, Ma, Shuang Yong, Chauhan, Abha, Chauhan, Ved, Miller, David L., Mehta, Pankaj D., Flory, Michael, Cohen, Ira L., London, Eric, Reisberg, Barry, de Leon, Mony J., Wisniewski, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342283/
https://ncbi.nlm.nih.gov/pubmed/22567102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035414
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