Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Screening chemical libraries to identify compounds that affect overall cell proliferation is common. However, in most cases, it is not known whether the compounds tested alter the timing of particular cell cycle transitions. Here, we evaluated an FDA-approved drug library to identify pharmaceuticals...

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Bibliografiske detaljer
Main Authors: Hoose, Scott A., Duran, Camille, Malik, Indranil, Eslamfam, Shabnam, Shasserre, Samantha C., Downing, S. Sabina, Hoover, Evelyn M., Dowd, Katherine E., Smith, Roger, Polymenis, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342239/
https://ncbi.nlm.nih.gov/pubmed/22567160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036503
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