Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Screening chemical libraries to identify compounds that affect overall cell proliferation is common. However, in most cases, it is not known whether the compounds tested alter the timing of particular cell cycle transitions. Here, we evaluated an FDA-approved drug library to identify pharmaceuticals...

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Autors principals: Hoose, Scott A., Duran, Camille, Malik, Indranil, Eslamfam, Shabnam, Shasserre, Samantha C., Downing, S. Sabina, Hoover, Evelyn M., Dowd, Katherine E., Smith, Roger, Polymenis, Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342239/
https://ncbi.nlm.nih.gov/pubmed/22567160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036503
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