Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Screening chemical libraries to identify compounds that affect overall cell proliferation is common. However, in most cases, it is not known whether the compounds tested alter the timing of particular cell cycle transitions. Here, we evaluated an FDA-approved drug library to identify pharmaceuticals...

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Detalhes bibliográficos
Main Authors: Hoose, Scott A., Duran, Camille, Malik, Indranil, Eslamfam, Shabnam, Shasserre, Samantha C., Downing, S. Sabina, Hoover, Evelyn M., Dowd, Katherine E., Smith, Roger, Polymenis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342239/
https://ncbi.nlm.nih.gov/pubmed/22567160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036503
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