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Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli 23S ribosomal RNA.

Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli ribosomes has been compared by chemical footprinting. The protection afforded by both drugs is limited to the peptidyl transferase loop of 23S rRNA. Under conditions of stoichiometric binding at 1 mM drug concentration i...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autor: Douthwaite, S
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1992
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.18.4717
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