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Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli 23S ribosomal RNA.
Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli ribosomes has been compared by chemical footprinting. The protection afforded by both drugs is limited to the peptidyl transferase loop of 23S rRNA. Under conditions of stoichiometric binding at 1 mM drug concentration i...
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| Autor principal: | |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1992
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334222/ https://ncbi.nlm.nih.gov/pubmed/1383931 |
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