EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors

BACKGROUND: Tristetraprolin (TTP) is a key mediator of processes such as inflammation resolution, the inhibition of autoimmunity and in cancer. It carries out this role by the binding and degradation of mRNA transcripts, thereby decreasing their half-life. Transcripts modulated by TTP encode protein...

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Hauptverfasser: Florkowska, Magdalena, Tymoszuk, Piotr, Balwierz, Aleksandra, Skucha, Anna, Kochan, Jakub, Wawro, Mateusz, Stalinska, Krystyna, Kasza, Aneta
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342124/
https://ncbi.nlm.nih.gov/pubmed/22433566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-8
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