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Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors

Autophagy is a cellular process leading to the degradation of cytoplasmic components such as organelles and intracellular pathogens. It has been shown that HIV-1 relies on several components of the autophagy pathway for its replication, but the virus also blocks late steps of autophagy to prevent it...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eekels, Julia JM, Sagnier, Sophie, Geerts, Dirk, Jeeninga, Rienk E, Biard-Piechaczyk, Martine, Berkhout, Ben
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342116/
https://ncbi.nlm.nih.gov/pubmed/22424437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-69
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