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Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA Reductase

BACKGROUND: Cholesterol is mainly synthesised in liver and the rate-limiting step is the reduction of 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) to mevalonate, a reaction catalysed by HMG-CoA reductase (HMGCR). There is a comprehensive body of evidence documenting that anabolic-androgenic steroi...

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Bibliografiske detaljer
Main Authors: Gårevik, Nina, Skogastierna, Cristine, Rane, Anders, Ekström, Lena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342114/
https://ncbi.nlm.nih.gov/pubmed/22433938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-597X-7-12
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