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The Interaction with H-2D(d) in cis is Associated with a Conformational Change in the Ly49A NK Cell Receptor

Mouse natural killer (NK) cells express Ly49 family receptors that recognize major histocompatibility complex class I (MHC-I) molecules. By interacting with MHC-I molecules expressed on other cells (in trans), inhibitory Ly49 receptors prevent the NK cell-mediated killing of normal cells. In additio...

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Autors principals: Back, Jonathan, Angelov, Georgi S., Mariuzza, Roy A., Held, Werner
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342051/
https://ncbi.nlm.nih.gov/pubmed/22566845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2011.00055
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