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Stable masking by H-2D(d) cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact

Ly49A is an inhibitory receptor, which counteracts natural killer (NK) cell activation on the engagement with H-2D(d) (D(d)) MHC class I molecules (MHC-I) on target cells. In addition to binding D(d) on apposed membranes, Ly49A interacts with D(d) ligand expressed in the plane of the NK cells'...

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Detalhes bibliográficos
Principais autores: Back, Jonathan, Chalifour, Anick, Scarpellino, Léonardo, Held, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820694/
https://ncbi.nlm.nih.gov/pubmed/17360463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607418104
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