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Effects of repeated oxycodone administration on its analgesic and subjective effects in normal, healthy volunteers

Tolerance to the analgesic effects of opioids has been demonstrated in laboratory animals after repeated drug administration, yet this effect has been studied less frequently under controlled laboratory conditions in humans. This within-subject, double-blind, placebo-controlled study was designed to...

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Detalhes bibliográficos
Main Authors: Cooper, Ziva D, Sullivan, Maria A, Vosburg, Suzanne K, Manubay, Jeanne M, Haney, Margaret, Foltin, Richard W, Evans, Suzette M, Kowalczyk, William J, Saccone, Phillip A, Comer, Sandra D
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341961/
https://ncbi.nlm.nih.gov/pubmed/22495183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e3283536d6f
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