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Molecular Mechanisms of Treg-Mediated T Cell Suppression
CD4(+)CD25(high)Foxp3(+) regulatory T cells (Tregs) can suppress other immune cells and, thus, are critical mediators of peripheral self-tolerance. On the one hand, Tregs avert autoimmune disease and allergies. On the other hand, Tregs can prevent immune reactions against tumors and pathogens. Despi...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Research Foundation
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341960/ https://ncbi.nlm.nih.gov/pubmed/22566933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00051 |
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