Amino Acid Position 11 of HLA-DRβ1 is a Major Determinant of Chromosome 6p Association with Ulcerative Colitis

The major histocompatibility complex (MHC) on chromosome 6p is an established risk locus for ulcerative colitis (UC) and Crohn’s disease (CD). We aimed to better define MHC association signals in UC and CD by combining data from dense single nucleotide polymorphism (SNP) genotyping and from imputati...

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Detalhes bibliográficos
Main Authors: Achkar, Jean-Paul, Klei, Lambertus, de Bakker, Paul I.W., Bellone, Gaia, Rebert, Nancy, Scott, Regan, Lu, Ying, Regueiro, Miguel, Brzezinski, Aaron, Kamboh, M. Ilyas, Fiocchi, Claudio, Devlin, Bernie, Trucco, Massimo, Ringquist, Steven, Roeder, Kathryn, Duerr, Richard H
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341846/
https://ncbi.nlm.nih.gov/pubmed/22170232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.79
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