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Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing.

Functional domains within the mammalian U2 snRNP particle that are required for pre-mRNA splicing have been analysed using antisense oligonucleotides. A comparison of the melting temperatures of duplexes formed between RNA and different types of antisense oligonucleotides has demonstrated that the m...

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Bibliografske podrobnosti
Main Authors: Barabino, S M, Sproat, B S, Lamond, A I
Format: Artigo
Jezik:Inglês
Izdano: 1992
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC334172/
https://ncbi.nlm.nih.gov/pubmed/1408748
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