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An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions.
Synthetic c-Ha-ras genes with an analogue of an abasic site in the first or the second position of codon 12, or in the second position of codon 61 were constructed and transfected into NIH3T3 cells. The genes with the lesions in codon 12 exhibited more focus formation than a normal c-Ha-ras gene, wh...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1992
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| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.17.4409 |
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