Cd14 SNPs Regulate the Innate Immune Response

CD14 is a monocytic differentiation antigen that regulates innate immune responses to pathogens. Here, we show that murine Cd14 SNPs regulate the length of Cd14 mRNA and CD14 protein translation efficiency, and consequently the basal level of soluble CD14 (sCD14) and type I IFN production by murine...

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Autors principals: Liu, Hong-Hsing, Hu, Yajing, Zheng, Ming, Suhoski, Megan M., Engleman, Edgar G., Dill, David, Hudnall, Matt, Wang, Jianmei, Spolski, Rosanne, Leonard, Warren J., Peltz, Gary
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341513/
https://ncbi.nlm.nih.gov/pubmed/22445606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.02.112
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