The glutathione disulfide mimetic, NOV-002, inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress

The oxidized glutathione mimetic NOV-002, is a unique anti-tumor agent that not only has the ability to inhibit tumor cell proliferation, survival, and invasion, but in some settings can also ameliorate cytotoxic chemotherapy-induced hematopoietic and immune suppression. However, the mechanisms by w...

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Bibliographische Detailangaben
Hauptverfasser: Diaz-Montero, C. Marcela, Wang, Yong, Shao, Lijian, Feng, Wei, Zidan, Abdel-Aziz, Pazoles, Christopher J., Montero, Alberto J., Zhou, Daohong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341494/
https://ncbi.nlm.nih.gov/pubmed/22343421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.02.007
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