Rd9 Is a Naturally Occurring Mouse Model of a Common Form of Retinitis Pigmentosa Caused by Mutations in RPGR-ORF15

Animal models of human disease are an invaluable component of studies aimed at understanding disease pathogenesis and therapeutic possibilities. Mutations in the gene encoding retinitis pigmentosa GTPase regulator (RPGR) are the most common cause of X-linked retinitis pigmentosa (XLRP) and are estim...

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Detalhes bibliográficos
Main Authors: Thompson, Debra A., Khan, Naheed W., Othman, Mohammad I., Chang, Bo, Jia, Lin, Grahek, Garrett, Wu, Zhijian, Hiriyanna, Suja, Nellissery, Jacob, Li, Tiansen, Khanna, Hemant, Colosi, Peter, Swaroop, Anand, Heckenlively, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341386/
https://ncbi.nlm.nih.gov/pubmed/22563472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035865
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