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Rescue of a H3N2 Influenza Virus Containing a Deficient Neuraminidase Protein by a Hemagglutinin with a Low Receptor-Binding Affinity

Influenza viruses possess at their surface two glycoproteins, the hemagglutinin and the neuraminidase, of which the antagonistic functions have to be well balanced for the virus to grow efficiently. Ferraris et al. isolated in 2003–2004 viruses lacking both a NA gene and protein (H3NA- viruses) (Fer...

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Autors principals: Richard, Mathilde, Erny, Alexandra, Caré, Bertrand, Traversier, Aurélien, Barthélémy, Mendy, Hay, Alan, Lin, Yi Pu, Ferraris, Olivier, Lina, Bruno
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341378/
https://ncbi.nlm.nih.gov/pubmed/22563453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033880
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