Rescue of a H3N2 Influenza Virus Containing a Deficient Neuraminidase Protein by a Hemagglutinin with a Low Receptor-Binding Affinity

Influenza viruses possess at their surface two glycoproteins, the hemagglutinin and the neuraminidase, of which the antagonistic functions have to be well balanced for the virus to grow efficiently. Ferraris et al. isolated in 2003–2004 viruses lacking both a NA gene and protein (H3NA- viruses) (Fer...

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Detalhes bibliográficos
Main Authors: Richard, Mathilde, Erny, Alexandra, Caré, Bertrand, Traversier, Aurélien, Barthélémy, Mendy, Hay, Alan, Lin, Yi Pu, Ferraris, Olivier, Lina, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341378/
https://ncbi.nlm.nih.gov/pubmed/22563453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033880
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