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Antiproliferative Effects of DNA Methyltransferase 3B Depletion Are Not Associated with DNA Demethylation

Silencing of genes by hypermethylation contributes to cancer progression and has been shown to occur with increased frequency at specific genomic loci. However, the precise mechanisms underlying the establishment and maintenance of aberrant methylation marks are still elusive. The de novo DNA methyl...

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Bibliografiska uppgifter
Huvudupphovsmän: Hagemann, Sabine, Kuck, Dirk, Stresemann, Carlo, Prinz, Florian, Brueckner, Bodo, Mund, Cora, Mumberg, Dominik, Sommer, Anette
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341356/
https://ncbi.nlm.nih.gov/pubmed/22563479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036125
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