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Human Gastric Mucins Differently Regulate Helicobacter pylori Proliferation, Gene Expression and Interactions with Host Cells

Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere. Mucin glycosylation differs between individuals and changes during disease...

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Bibliografische gegevens
Hoofdauteurs: Skoog, Emma C., Sjöling, Åsa, Navabi, Nazanin, Holgersson, Jan, Lundin, Samuel B., Lindén, Sara K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341350/
https://ncbi.nlm.nih.gov/pubmed/22563496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036378
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