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Human Gastric Mucins Differently Regulate Helicobacter pylori Proliferation, Gene Expression and Interactions with Host Cells

Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere. Mucin glycosylation differs between individuals and changes during disease...

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Detalhes bibliográficos
Main Authors: Skoog, Emma C., Sjöling, Åsa, Navabi, Nazanin, Holgersson, Jan, Lundin, Samuel B., Lindén, Sara K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341350/
https://ncbi.nlm.nih.gov/pubmed/22563496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036378
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