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BabA dependent binding of Helicobacter pylori to human gastric mucins cause aggregation that inhibits proliferation and is regulated via ArsS

Mucins in the gastric mucus layer carry a range of glycan structures, which vary between individuals, can have antimicrobial effect or act as ligands for Helicobacter pylori. Mucins from various individuals and disease states modulate H. pylori proliferation and adhesin gene expression differently....

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Skoog, Emma C., Padra, Médea, Åberg, Anna, Gideonsson, Pär, Obi, Ikenna, Quintana-Hayashi, Macarena P., Arnqvist, Anna, Lindén, Sara K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247751/
https://ncbi.nlm.nih.gov/pubmed/28106125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40656
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