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The p53 isoforms are differentially modified by Mdm2
The discovery that the single p53 gene encodes several different p53 protein isoforms has initiated a flurry of research into the function and regulation of these novel p53 proteins. Full-length p53 protein level is primarily regulated by the E3-ligase Mdm2, which promotes p53 ubiquitination and deg...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341231/ https://ncbi.nlm.nih.gov/pubmed/22487680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20119 |
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