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p53 Isoforms: An Intracellular Microprocessor?

Normal function of the p53 pathway is ubiquitously lost in cancers either through mutation or inactivating interaction with viral or cellular proteins. However, it is difficult in clinical studies to link p53 mutation status to cancer treatment and clinical outcome, suggesting that the p53 pathway i...

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Bibliographic Details
Main Authors: Khoury, Marie P., Bourdon, Jean-Christophe
Format: Artigo
Language:Inglês
Published: SAGE Publications 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135639/
https://ncbi.nlm.nih.gov/pubmed/21779513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408893
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