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p53 Isoforms: An Intracellular Microprocessor?

Normal function of the p53 pathway is ubiquitously lost in cancers either through mutation or inactivating interaction with viral or cellular proteins. However, it is difficult in clinical studies to link p53 mutation status to cancer treatment and clinical outcome, suggesting that the p53 pathway i...

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Autors principals: Khoury, Marie P., Bourdon, Jean-Christophe
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135639/
https://ncbi.nlm.nih.gov/pubmed/21779513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408893
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