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Multiple components are involved in the efficient joining of double stranded DNA breaks in human cell extracts.
We describe a rapid and efficient in vitro system for the rejoining of double stranded breaks in DNA based on extracts of human 293 cells. Using this system as an assay, we have separated the nuclear extract into several components involved in break rejoining. The unfractionated system can convert a...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1992
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508709/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.16.4145 |
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