The R337H mutation in TP53 and breast cancer in Brazil

BACKGROUND: Germline mutations in p53 are associated with the Li-Fraumeni Syndrome which is characterized by childhood cancers, including pediatric adrenal cortical carcinomas and early onset breast cancer. The high incidence of adrenal cortical carcinomas in southern Brazil is mostly attributed to...

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Detalhes bibliográficos
Main Authors: Gomes, Magda CB, Kotsopoulos, Joanne, de Almeida, Gutemberg Leão, Costa, Mauricio M, Vieira, Roberto, Filho, Firmino de AG, Pitombo, Marcos B, F Leal, Paulo Roberto, Royer, Robert, Zhang, Phil, Narod, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341178/
https://ncbi.nlm.nih.gov/pubmed/22455664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-10-3
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