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Kinetic Mechanism of Initiation by RepD as a Part of Asymmetric, Rolling Circle Plasmid Unwinding

[Image: see text] Some bacterial plasmids carry antibiotic resistance genes and replicate by an asymmetric, rolling circle mechanism, in which replication of the two strands is not concurrent. Initiation of this replication occurs via an initiator protein that nicks one DNA strand at the double-stra...

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Bibliografiske detaljer
Main Authors: Arbore, Claudia, Lewis, Lori M., Webb, Martin R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2012
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340939/
https://ncbi.nlm.nih.gov/pubmed/22463759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300172p
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