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Extensive DNA Damage-Induced Sumoylation Contributes to Replication and Repair and Acts in Addition to the Mec1 Checkpoint

The cellular response to DNA damage employs multiple dynamic protein modifications to exert rapid and adaptable effects. Substantial work has detailed the roles of canonical checkpoint-mediated phosphorylation in this program. Recent studies have also implicated sumoylation in the DNA damage respons...

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Autori principali: Cremona, Catherine A., Sarangi, Prabha, Yang, Yan, Hang, Lisa E., Rahman, Sadia, Zhao, Xiaolan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340930/
https://ncbi.nlm.nih.gov/pubmed/22285753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.028
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