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Extensive DNA Damage-Induced Sumoylation Contributes to Replication and Repair and Acts in Addition to the Mec1 Checkpoint

The cellular response to DNA damage employs multiple dynamic protein modifications to exert rapid and adaptable effects. Substantial work has detailed the roles of canonical checkpoint-mediated phosphorylation in this program. Recent studies have also implicated sumoylation in the DNA damage respons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cremona, Catherine A., Sarangi, Prabha, Yang, Yan, Hang, Lisa E., Rahman, Sadia, Zhao, Xiaolan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340930/
https://ncbi.nlm.nih.gov/pubmed/22285753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.028
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