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Exon sequences distant from the splice junction are required for efficient self-splicing of the Tetrahymena IVS.

The presence of a natural rRNA secondary structure element immediately preceding the 5' splice site of the Tetrahymena IVS can inhibit self-splicing by competing with base pairing between the 5' exon and the guide sequence of the IVS (P1). Formation of this alternative hairpin is preferred...

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Bibliografiske detaljer
Hovedforfatter: Woodson, S A
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334083/
https://ncbi.nlm.nih.gov/pubmed/1508687
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