Exon sequences distant from the splice junction are required for efficient self-splicing of the Tetrahymena IVS.
The presence of a natural rRNA secondary structure element immediately preceding the 5' splice site of the Tetrahymena IVS can inhibit self-splicing by competing with base pairing between the 5' exon and the guide sequence of the IVS (P1). Formation of this alternative hairpin is preferred in short...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1992
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.15.4027 |
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