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Exon sequences distant from the splice junction are required for efficient self-splicing of the Tetrahymena IVS.
The presence of a natural rRNA secondary structure element immediately preceding the 5' splice site of the Tetrahymena IVS can inhibit self-splicing by competing with base pairing between the 5' exon and the guide sequence of the IVS (P1). Formation of this alternative hairpin is preferred...
Bewaard in:
| Hoofdauteur: | |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1992
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334083/ https://ncbi.nlm.nih.gov/pubmed/1508687 |
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