In vitro replication of bacteriophage PRD1 DNA. Metal activation of protein-primed initiation and DNA elongation.
Bacteriophage PRD1 replicates its DNA by means of a protein-primed replication mechanism. Compared to Mg2+, the use of Mn2+ as the metal activator of the phage DNA polymerase results in a great stimulation of the initiation reaction. The molecular basis of the observed stimulatory effect is an incre...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1992
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.15.3971 |
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