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In vitro replication of bacteriophage PRD1 DNA. Metal activation of protein-primed initiation and DNA elongation.

Bacteriophage PRD1 replicates its DNA by means of a protein-primed replication mechanism. Compared to Mg2+, the use of Mn2+ as the metal activator of the phage DNA polymerase results in a great stimulation of the initiation reaction. The molecular basis of the observed stimulatory effect is an incre...

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Autors principals: Caldentey, J, Blanco, L, Savilahti, H, Bamford, D H, Salas, M
Format: Artigo
Idioma:Inglês
Publicat: 1992
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC334074/
https://ncbi.nlm.nih.gov/pubmed/1324473
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