Bis(7)-tacrine protects retinal ganglion cells against excitotoxicity via NMDA receptor inhibition

AIM: To investigate whether bis(7)-tacrine, a multifunctional drug, inhibits N-methyl-D-aspartate (NMDA) -activated current in retinal ganglion cells(RGC) and provides neuroprotection against retinal cell damage. METHODS: Purified RGC cultures were obtained from retinas of 1-3 days old Sprague-Dawle...

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Bibliografske podrobnosti
Main Authors: Zhang, Zu-Hai, Liu, Yu-Wei, Jiang, Fa-Gang, Tian, Xiang, Zhu, Yan-Hua, Li, Jing-Bo, Wang, Qi, Fang, Jia-Hua
Format: Artigo
Jezik:Inglês
Izdano: International Journal of Ophthalmology Press 2011
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340694/
https://ncbi.nlm.nih.gov/pubmed/22553626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2011.02.03
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