Lactate uptake contributes to the NAD(P)H biphasic response and tissue oxygen response during synaptic stimulation in area CA1 of rat hippocampal slices

Synaptic train stimulation (10 Hz × 25 s) in hippocampal slices results in a biphasic response of NAD(P)H fluorescence indicating a transient oxidation followed by a prolonged reduction. The response is accompanied by a transient tissue PO(2) decrease indicating enhanced oxygen utilization. The acti...

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Detalhes bibliográficos
Main Authors: Galeffi, Francesc, Foster, Kelley A, Sadgrove, Matthew P, Beaver, Christopher J, Turner, Dennis A
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340603/
https://ncbi.nlm.nih.gov/pubmed/17931363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.04939.x
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