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Unsupervised pattern discovery in human chromatin structure through genomic segmentation
We applied a dynamic Bayesian network method that identifies joint patterns from multiple functional genomics experiments to ChIP-seq histone modification and transcription factor data, and DNaseI-seq and FAIRE-seq open chromatin readouts from the human cell line K562. In an unsupervised fashion, we...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340533/ https://ncbi.nlm.nih.gov/pubmed/22426492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1937 |
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