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Unsupervised pattern discovery in human chromatin structure through genomic segmentation

We applied a dynamic Bayesian network method that identifies joint patterns from multiple functional genomics experiments to ChIP-seq histone modification and transcription factor data, and DNaseI-seq and FAIRE-seq open chromatin readouts from the human cell line K562. In an unsupervised fashion, we...

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Detalhes bibliográficos
Main Authors: Hoffman, Michael M., Buske, Orion J., Wang, Jie, Weng, Zhiping, Bilmes, Jeff A., Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340533/
https://ncbi.nlm.nih.gov/pubmed/22426492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1937
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