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The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine
BACKGROUND: Relapse to cocaine-seeking has been linked with low glutamate in the nucleus accumbens core (NAcore) causing potentiation of synaptic glutamate transmission from prefrontal cortex (PFC) afferents. Systemic N-acetylcysteine (NAC) has been shown to restore glutamate homeostasis, reduce rel...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340445/ https://ncbi.nlm.nih.gov/pubmed/22137594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.10.024 |
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