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Naïve T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel T helper type 2 immunity
BACKGROUND: Sensitization to protease allergens, such as papain, or helminth infection is associated with basophil recruitment to draining lymph nodes. Basophils have the capacity to present antigen to naïve T cells and promote T(H)2 differentiation directly or indirectly through IL-4 production. OB...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340436/ https://ncbi.nlm.nih.gov/pubmed/22460072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.02.035 |
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