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Implications of Altered Glutathione Metabolism in Aspirin-Induced Oxidative Stress and Mitochondrial Dysfunction in HepG2 Cells

We have previously reported that acetylsalicylic acid (aspirin, ASA) induces cell cycle arrest, oxidative stress and mitochondrial dysfunction in HepG2 cells. In the present study, we have further elucidated that altered glutathione (GSH)-redox metabolism in HepG2 cells play a critical role in ASA-i...

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Sonraí Bibleagrafaíochta
Main Authors: Raza, Haider, John, Annie
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340360/
https://ncbi.nlm.nih.gov/pubmed/22558435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036325
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