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Streptozotocin-Induced Cytotoxicity, Oxidative Stress and Mitochondrial Dysfunction in Human Hepatoma HepG2 Cells

Streptozotocin (STZ) is an antibiotic often used in the treatment of different types of cancers. It is also highly cytotoxic to the pancreatic beta-cells and therefore is commonly used to induce experimental type 1 diabetes in rodents. Resistance towards STZ-induced cytotoxicity in cancer cells has...

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Bibliografiske detaljer
Main Authors: Raza, Haider, John, Annie
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382802/
https://ncbi.nlm.nih.gov/pubmed/22754329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13055751
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